Choose Me+ to improve physical and mental health, promote weight loss, experience anti-aging benefits, and more through developing healthy daily habits and self-care routines. Fill your days with. ME definition: the objective case of I, used as a direct or indirect object. See examples of me used in a sentence. ME is a long-lasting illness that is thought to be caused by a virus. Its symptoms include feeling tired all the time and muscle pain. ME is an abbreviation for 'myalgic encephalomyelitis'. The ME made it hard. Collins COBUILD Advanced Learner’s Dictionary. Copyright © HarperCollins Publishers. We use I and me to refer to the speaker or writer. I is the subject form and me is the object form: … Knowing when to use me versus I can be tricky. Learn when to use I or me so your sentences are always clear and correct. Messenger helps you connect with your Facebook friends and family, build your community, and deepen your interests. Me is used in many places where strict grammarians require I. In truth, this has less to do with grammar and more to do with the fact that me has been gradually replacing I since around the 16th century largely because of the pressure of word order.